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See you in Chicago!
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ACO staff will be in Chicago, USA for the HIV Research for Prevention (HIV R4P) Conference (October 17 – 21, 2016). We will be hosting a satellite session and an invitation-only Canadian Networking Breakfast, where Canadian researchers will have a chance to give one-minute elevator pitches on their research. Read more below about details on upcoming activities. We look forward to seeing you in Chicago!
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HIV R4P Satellite Session: Beyond Viral
Neutralization
Friday, October 21, 2016 | 9:00 am to 12:00 pm
Sheraton Grand Chicago, Sheraton Ballroom III
The ACO is pleased to help facilitate a satellite session at the HIV R4P Conference in Chicago. This satellite session aims to bring the scientific community together to discuss the latest developments in the expanding field of non-neutralizing, effector function competent (nNeFC) anti-HIV-1 antibodies.
Read more about ACO activities at HIV R4P.
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Global HIV Vaccine Enterprise: 2nd Env Vaccine Manufacturing Workshop
Thursday, September 15, 2016 | 8:30 am to 4:15 pm
NIAID Headquarters, Rockville, Maryland, USA
The Second HIV Envelope Manufacturing Workshop follows up on the successful 2015 meeting, which for the first time gathered key world experts to discuss issues related to manufacturing recombinant subunit Env proteins to be used as immunogens for clinical testing of candidate HIV-1 vaccines. More Information.
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Building the Alliance: ACO Annual Update 2015-2016
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Want to know what the ACO has been up to? The annual report offers highlights of ACO activities over the past fiscal year.
Scan the QR code to read the annual update on your mobile, or view it on your desktop. French version available upon request, email aco@icid.com.
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Peer Review Working Group Established to Advise CIHR
CIHR (www.cihr.gc.ca), July 22, 2016
As a follow-up to the outcomes of the July 13th Working Meeting to discuss CIHR's peer review processes, a Peer Review Working Group has been established under the leadership of Dr. Paul Kubes as Executive Chair of the College of Reviewers.
READ MORE
Vaginal Bacteria Species Can Raise HIV Infection Risk and Undermine Prevention
Science (www.sciencemag.org), July 18, 2016
Jon Cohen
The new findings all come from follow-up studies of women who participated in a PrEP study of a vaginal gel that contained the anti-HIV drug tenofovir. Conducted by the Centre for the AIDS Programme of Research in South Africa (CAPRISA) based in Durban, the trial took place in a region where 66% of 30-year-old women are infected.
READ MORE
An HIV Vaccine – Mapping Uncharted Territory
JAMA. 2016;316(2):143-144. doi:10.1001/jama.2016.7538.
Anthony S. Fauci, MD
In this Viewpoint, Anthony Fauci summarizes progress to date in efforts to develop an HIV vaccine that induces broadly neutralizing antibodies to neutralize the range of HIV variants that emerge from rapid mutations.
READ MORE
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New Research
Envelope-specific B-cell Populations in African Green Monkeys Chronically Infected with Simian Immunodeficiency Virus.
Nat Common. 2016 Jul 6;7:12131. doi: 10.1038/ncomms12131.
Zhang R, Martinez DR, Nguyen QN, Pollara J, et al.
African green monkeys (AGMs) are natural primate hosts of simian immunodeficiency virus (SIV). Interestingly, features of the envelope-specific antibody responses in SIV-infected AGMs are distinct from that of HIV-infected humans and SIV-infected rhesus monkeys, including gp120-focused responses and rapid development of autologous neutralization.
READ MORE
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A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability.
J Virol. 2016 Jul 6. pii: JVI.01068-16. [Epub ahead of print]
Ding S, Tolbert WD, Prévost J, Pacheco B, et al.
Here, we show that W69, located at the interface between the gp120 and the gp41 in the PGT151-bound trimer, plays a critical role in the inter-protomer signaling induced by CD4 binding. This new information might be useful in immunogen design.
READ MORE
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Prevalence of Sexually Transmitted Viral and Bacterial Infections in HIV-Positive and HIV-Negative Men Who Have Sex with Men in Toronto.
PLoS One. 2016 Jul 8;11(7):e0158090. doi: 10.1371/journal.pone.0158090.
Remis RS, Lui H, Loutfy MR, Tharao W, et al.
Syphilis and viral infections, including HBV, HCV, HSV-2, CMV, and HR-HPV, were common in this clinic-based population of MSM in Toronto and more frequent among MSM living with HIV. This argues for the implementation of routine screening, vaccine-based prevention, and education programs in this high-risk population.
READ MORE
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Employment Opportunity
Dr. Jérôme Estaquier's Laboratory - Centre de Recherche du CHUQ, Axe Maladies infectieuses et immunitaires, Centre Hospitalier de l'Université Laval
The objective of our research project is to carry out a comparative study between the infection of myeloid cells and the different subpopulations of CD4 T cells, named naïve, central memory, effector memory, T follicular helper, and terminally differentiated cells, in lymphoid tissues from macaques under antiretroviral therapy, to better understand the mechanisms related to treatment failure and HIV persistence.
MORE INFORMATION
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Conferences
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October 11 to 14, 2016
34th Annual Symposium on Nonhuman Primate Models for AIDS
New Orleans, USA
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October 17 to 20, 2016
HIV Research for Prevention
Chicago, USA
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October 24 to 26, 2016
OHTN Conference Series: Conference 1 – Closing the Gaps in the Care Cascade
Toronto, CA
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November 21 to 22, 2016
OHTN Conference Series: Conference 2 – Stopping the Syndemics that Drive HIV
Toronto, CA
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December 3 to 4, 2016
National HIV PrEP Summit
San Francisco, USA
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December 6 to 8, 2016
12th Canadian Immunization Conference (CIC 2016)
Ottawa, CA
See full list of conferences
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About Us
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The ACO was established by the Government of Canada and the Bill & Melinda Gates Foundation in November 2011 at the International Centre for Infectious Diseases (ICID), a
not-for-profit,
non-governmental organization based in Winnipeg.
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Connect With Us:
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ACO at
International Centre for Infectious Diseases
515 Portage Avenue
Winnipeg, MB, Canada
R3B 2E9
Tel.: 204 946 0908
Fax: 204 946 0927
email:
aco@icid.com
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